GABA Supplements Review

What did CL's tests and review of GABA supplements show?

What is the best GABA supplement?

How to take GABA?

GABA safety and side effects:

In addition the results of its expert testing, ConsumerLab uses only high-quality, evidence based, information sources. These sources include peer-reviewed studies and information from agencies such as the FDA and USDA, and the National Academy of Medicine. On evolving topics, studies from pre-print journals may be sourced. All of our content is reviewed by medical doctors and doctoral-level experts in pharmacology, toxicology, and chemistry. We continually update and medically review our information to keep our content trustworthy, accurate, and reliable. The following sources are referenced in this article:

• Hepsomali, Front Neurosci 2020
• Petroff, Ann Neurol 1996
• Boonstra, Front Psychol 2015
• Byun, J Clin Neurol 2018
• Yamatsu, Food Sci Biotechnol 2016
• Guimarães, J Diet Suppl 2024
• Winkelman, Sleep Med 2014
• Abdou, Biofactors 2006
• Yoto, Amino Acids 2012
• Natural Health Products Ingredients Database, Health Canada, 2021
• Murari, Cerebral Cortex Comm 2020
• Steenbergen, Sci Rep 2015
• Lim, J Clin Med 2021
• Inoue, Eur J Clin Nutr 2003
• Shimada, Clin Exp Hypertens 2009
• Powers, Med Sci Sports Exerc 2008
• Sakashita, J Clin Med Res 2019
• Sanacora, Am J Psychiatry 2002

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GABA (gamma-aminobutyric acid) supplement brands compared in this review

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BrainMD By Daniel Amen, MD GABA Calming Support

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BulkSupplements.com Gamma Aminobutyric Acid (GABA)

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Designs For Health Liposomal NeuroCalm

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GNC GABA

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KAL GABA 25 mg - Cherry Natural Flavor

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Natural Factors Pharma GABA

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NOW GABA 500 mg

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NVS Labs GABA

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Solgar GABA 500 mg

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Source Naturals GABA Calm

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Swanson GABA

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Thorne PharmaGABA-100

You must be a member to get the full test results along with ConsumerLab.com recommendations and quality ratings. You will get results for 10 GABA (gamma-aminobutyric acid) supplements selected for testing by ConsumerLab.com, as well as two other products that are included for having passed the same testing through ConsumerLab's voluntary Quality Certification Program. In this comprehensive review, you'll discover:

• What GABA (gamma-aminobutyric acid) is and whether GABA supplements provide any health benefits
• Which GABA supplements passed or failed ConsumerLab's tests of quality
• ConsumerLab's Top Picks for low, moderate, and high-dose GABA supplements based on quality, value, and for powders and liquids, taste
• The clinical evidence for and against GABA supplements for lowering blood pressure, reducing stress, improving sleep, and improving memory and cognition

• The difference between "biosynthetic" and "synthetic GABA, and information about branded GABA ingredients such as PharmaGABA (Pharma Foods International Japan)
• The best way to take GABA supplements
• Foods that may contain GABA
• Safety and potential side effects and drug interactions with GABA (gamma-aminobutyric acid) supplements

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Latest Clinical Research Updates for GABA Supplements

GABA for Sleep or Mood?

May 14, 2024

The authors of a recent study suggested that taking GABA before bedtime enhanced sleep efficiency, but we question whether it really helped at all, as discussed in the Insomnia section of our GABA Supplements Review, which includes our Top Picks among GABA supplements.

Solgar GABA Approved

May 16, 2023

Solgar GABA 500 mg was recently tested and Approved through our voluntary Quality Certification Program and was added to our GABA Supplements Review.

Restless Leg Syndrome: GABA vs Gabapentin

May 05, 2023

One of these can help with restless leg syndrome, while the other doesn’t. Learn the difference in our GABA Supplements Review, which includes our Top Picks for GABA.

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Tested through CL's Quality Certification Program prior to, or after initial posting of this Product Review.

The "Updated" date indicates when new clinical or product information was most recently added. In the full review (available to CL members), the newest information is highlighted in yellow and, if a new product is added, it is footnoted in the results table, showing the date added to the review.